Research publications

The MOX is a validated and medically certified wearable accelerometer that delivers one of the most precise and consistent measurements for physical activity monitoring. It is the most advanced accelerometer development from Maastricht Instruments BV based on the earlier product versions, the CIRO Activity Monitor (CAM) and DAAFb which have been used for more than a decade to accurately measure physical activity in research and healthcare applications.

The publications are sorted by topic. The entire list can be viewed by clicking on next below the list.

AuthorsYear of PublicationTitleJournalTopicKeywordsDOI link
Irene Moll, Rik G. J. Marcellis, Marcel L. P. Coenen, Sabine M. Fleuren, Paul J. B. Willems, Lucianne A. W. M. Speth, M. Adhiambo Witlox, Kenneth Meijer & R. Jeroen Vermeulen 2022A randomized crossover study of functional electrical stimulation during walking in spastic cerebral palsy: the FES on participation (FESPa) trialBMCCerebral palsy, Spasticity, Gait, Orthoses, Functional electrical stimulation, Goal attainment scale
Ayan Chatterjee, Andreas Prinz2022Applying Spring Security Framework with KeyCloak-Based OAuth2 to Protect Microservice Architecture APIs: A Case Study
Data Security
API;REST;spring-boot;Keycloak;authentication;authorization;encryption;external attacks
Hanneke C. van Dijk-Huisman,Mandy H. P. Welters,Wouter Bijnens,Sander M. J. van Kuijk,Fabienne J. H. Magdelijns,Robert A. de Bie, Antoine F. Lenssen
2022Can telerehabilitation services combined with caregiver-mediated exercises improve early supported discharge services poststroke? A study protocol for a multicentre, observer-blinded, randomized controlled trial
BMC Neurology
Stroke, Telerehabilitation, Caregivers, Exercise, Walking, Clinical trial protocol
Kyra Theunissen, Bas Van Hooren, Guy Plasqui, Kenneth Meijer2022Dataset of energetics and biomechanics of self-paced and fixed speed treadmill walking at multiple speedsScienceDirectGait Biomechanics Energy cost of walking Self-paced treadmillEnergy expenditure Kinematics
Hanneke C. van Dijk-Huisman, Mandy H. P. Welters, Wouter Bijnens, Sander M. J. van Kuijk, Fabienne J. H. Magdelijns, Robert A. de Bie & Antoine F. Lenssen 2022Development and internal validation of a prediction model to identify older adults at risk of low physical activity levels during hospitalisation: a prospective cohort studyBMC GeriatricsPhysical activity, Hospital, Prediction model, Older adults
Hanneke C. van Dijk-Huisman, Mandy H. P. Welters,Wouter Bijnens, Sander M. J. van Kuijk, Fabienne J. H. Magdelijns, Robert A. de Bie, Antoine F. Lenssen
2022Development and internal validation of a prediction model to identify older adults at risk of low physical activity levels during hospitalisation: a prospective cohort study
BMC Geriatrics
Physical activity, Hospital, Prediction model, Older adults
Annemarijn Weber,corresponding author Stephanie M D Huysmans, Sander M J van Kuijk, Silvia M A A Evers, Elisabeth M C Jutten, Rachel Senden, Aggie T G Paulus, Joop P W van den Bergh, Rob A de Bie, Johannes M R Merk, Sandrine P G Bours, Mark Hulsbosch,Esther R C Janssen, Inez Curfs, Wouter L W van Hemert, Martijn G M Schotanus,Paul de Baat, Niek C Schepel, Willem A den Boer, Johannes G E Hendriks,Wai-Yan Liu,Marinus de Kleuver, Martin H Pouw, Miranda L van Hooff, Eva Jacobs, and Paul C P H Willems2022Effectiveness and cost-effectiveness of dynamic bracing versus standard care alone in patients suffering from osteoporotic vertebral compression fractures: protocol for a multicentre, two-armed, parallel-group randomised controlled trial with 12 months of follow-upBMJ Openorthopaedic & trauma surgery, back pain, bone diseases, spine
Dieuwke van Dartel, Johannes H. Hegeman, Miriam M. R. Vollenbroek-Hutten2022Feasibility and Usability of Wearable Devices for Ambulatory Monitoring of the Rehabilitation Process of Older Patients after Hip Fracture SurgeryResearch Information System Wearable Devices, Ambulatory Monitoring, Fitbit, MOX, Feasibility, Usability, Older Patients, Hip Fracture.
Marlou-Floor Kenkhuis, Eline H. van Roekel, Janna L. Koole, Jos? J.L. Breedveld-Peters,St?phanie O. Breukink, Maryska L.G. Janssen-Heijnen, Eric T.P. Keulen, Fr?nzel J.B. van Duijnhoven, Floortje Mols, Matty P. Weijenberg , Martijn J.L. Bours2022Increases in adipose tissue and muscle function are longitudinally associated with better quality
of life in colorectal cancer survivors
NatureCancer, Cancer epidemiology, Gastrointestinal cancer
Līna Butāne, Liene Spilva-Ekerte, Andris Skride, Daina Šmite 2022Individually Tailored Remote Physiotherapy Program Improves Participation and Autonomy in Activities of Everyday Life along with Exercise Capacity, Self-Efficacy, and Low-Moderate Physical Activity in Patients with Pulmonary Arterial Hypertension: A Randomized Controlled StudyMedicinaRehabilitationchronic disease;pulmonary arterial hypertension;physiotherapy; individualized; interdisciplinary; quality of life;participation;exercise;physical activity;home-based;self-efficacy
Wouter van Marken Lichtenbelt, Hannah Pallubinsky, Rick Kramer2022Learning communities, installation sector, energy transition, professional developmentCLIMAhealth, comfort, resilience, energy
Marlou-Floor Kenkhuis,Eline H. van Roekel ,Jos? J. L. Breedveld-Peters,St?phanie O. Breukink,Maryska L. G. Janssen-Heijnen ,Eric T. P. Keulen ,Fr?nzel J. B. van Duijnhoven ,Matty P. Weijenberg andMartijn J. L. Bours2022Longitudinal Associations of Adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) Lifestyle Recommendations with Quality of Life and Symptoms in Colorectal Cancer Survivors up to 24 Months Post-TreatmentMDPIcolorectal cancer survivorship; lifestyle recommendations; health-related quality of life; fatigue; chemotherapy-induced peripheral neuropathy
Marlou-Floor Kenkhuis, Floortje Mols,Eline H. van Roekel, Jos? J. L. Breedveld-Peters, St?phanie Breukink, Maryska Janssen-Heijnen,Eric Keulen, Fr?nzel J. van Duijnhoven,Matty P. Weijenberg2022Longitudinal associations of fast foods, red and processed meat, alcohol and sugar-sweetened drinks with quality of life and symptoms in colorectal cancer survivors up to 24 months post-treatmentCambridge UniversityColorectal cancer survivorship, Lifestyle recommendation, Diet, Health-related, quality of life, Fatigue, Chemotherapy-induced peripheral neuropathy
Eline H. van Roekel,Martijn J. L. Bours,St?phanie O. Breukink,Mich?l Aquarius,Eric T. P. Keulen,Audrey Gicquiau,Sabina Rinaldi,Paolo Vineis,Ilja C. W. Arts,Marc J. Gunter,Michael F. Leitzmann,Augustin Scalbert,Matty P. Weijenberg2022Longitudinal associations of plasma metabolites with persistent fatigue among colorectal cancer survivors up to 2 years after treatmentWiley Online Libraryamino acids, cancer-related fatigue, colorectal cancer, phospholipids targeted metabolomics
Marlou-Floor Kenkhuis, Mo Klingestijn, Anne-Marie Fanshawe, St?phanie O. Breukink, Maryska L. G. Janssen-Heijnen, Eric T. P. Keulen, Sabina Rinaldi, Paolo Vineis, Marc J. Gunter, Michael F. Leitzmann, Augustin Scalbert, Matty P. Weijenberg, Martijn J. L. Bours & Eline H. van Roekel 2022Longitudinal associations of sedentary behavior and physical activity with body composition in colorectal cancer survivors up to 2 years post treatmentSpringer Nature Switzerland Physical activity. Sedentary behavior, Body composition, Colorectal cancer survivors
Ayan Chatterjee, Nibedita Pahari, Andreas Prinz & Michael Riegler 2022Machine learning and ontology in eCoaching for personalized activity level monitoring and recommendation generationSpringer Nature LimitedHealth care, Mathematics and computing
Dieuwke van Dartel, Ying Wang, Johannes H. Hegeman, Marloes Vermeer, Miriam M.R. Vollenbroek-Hutten2022Patterns of Physical Activity Over Time in Older Patients Rehabilitating after Hip Fracture Surgery: A Preliminary StudymedRxivPhysical activity, rehabilitation medicine
Ayan Chatterjee, Andreas Prinz, Martin Gerdes, Santiago Martinez, Nibedita Pahari, Yogesh Kumar Meena
2022ProHealth eCoach: User-Centered Design and Development of an eCoach App to Promote Healthy Lifestyle with Personalized Activity Recommendations
Research Square (Preprint)
eHealth Application
eCoach, User-Centered Design, Persuasive Strategies, Visualisation, Healthy Lifestyle, Physical Activity
Simon Higgins, Emma S.Cowley, CraigPaterson, Erik D.Hanson, Gaurav J.Daveb Michelle L.Meyercd Feng-Chang Line Bethany Barone Gibbsf Maihan Vug Lee Stonerad2022Protocol for a study on sitting with interruption and whole-body cardiovascular health (SWITCH) in middle-aged adultsScienceDirectSedentary behaviorArterial stiffnessCardiovascularPathophysiologyPublic policy
Jeroen G. V. Habets, Margot Heijmans, Albert F. G. Leentjens, Claudia J. P. Simons, Yasin Temel, Mark L. Kuijf, Pieter L. Kubben, Christian Herff2021A Long-Term, Real-Life Parkinson Monitoring Database Combining Unscripted Objective and Subjective RecordingsDataParkinson’s disease; real-life; unscripted; naturalistic monitoring; wearable sensors; motor diaries; ecological momentary assessments; experience sampling method10.3390/data6020022
Marlou-Floor Kenkhuis ,Bernadette W. A. van der Linden,Jose J. L. Breedveld-PetersJanna L. Koole,Eline H. van Roekel,St?phanie O. Breukin,Floortje Mols,Matty P. Weijenberg Martijn J. L. Bours2021Associations of the dietary World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) recommendations with patient-reported outcomes in colorectal cancer survivors 2–10 years post-diagnosis: a cross-sectional analysisCambridge University PressColorectal cancer survivorship Lifestyle recommendations, Diet, Health-related, quality of life, Fatigue, Neuropathy
Xu, Huimei; Wang, Wancong; Ma, Xueni; Feng, Rukun; Su, Yujing; Cheng, Long; Yang, Yifan; Zhang, Dekui2021Comparative efficacy and safety of high-dose dual therapy, bismuth-based quadruple therapy and non-bismuth quadruple therapies for Helicobacter pylori infection: a network meta-analysisIngenta ConnectHelicobacter pylori; eradication; first-line therapy; network meta-analysis
Henrique Marcos, Antonia Waltermann, Jaap Hage2021From Sovereignty to International Cooperation: Lessons from Legal Logic and Social OntologySSRNFragmentation of international law; State sovereignty; logic of rules; rule conflicts; rule consistency; social ontology
Kenkhuis, MF, van Roekel EH, Koole JL, Breedveld-Peters JJL, Breukink SO, Janssen-Heijnen MLG, Keulen ETP, van Duijnhoven FJB, Mols F, Weijenberg MP, Bours MJL2021Increases in adipose tissue and muscle function are longitudinally associated with better quality of life in colorectal cancer survivorsScientific ReportsCancer Survivors/psychology, Colorectal Neoplasms/complications, Longitudinal Studies, Quality of Life10.1038/s41598-021-91709-y
Sophie Vanbelle, Emmanuel Lesaffre2021Modelling agreement for binary intensive longitudinal dataStatistical Modellingcontinuous recording,?Reliability,?time-event sequential data,?time series,?transient event10.1177/1471082X211034002
Elena Xu ,David P?rez-Torres ,Paraskevi C. Fragkou ,Jean-Ralph Zahar andDespoina Koulenti2021Nosocomial Pneumonia in the Era of Multidrug-Resistance: Updates in Diagnosis and ManagementMDPInosocomial pneumonia; hospital-acquired pneumonia; ventilator-associated pneumonia; lung ultrasound; low-radiation CT; rapid microbiological diagnosis; syndromic multiplex PCR panels; novel antibiotics
Hanneke C. van Dijk-Huisman, Wouter Bijnens, Rachel Senden, Johannes M. N. Essers, Kenneth Meijer, Jos Aarts, Antoine F. Lenssen2021Optimization and Validation of a Classification Algorithm for Assessment of Physical Activity in Hospitalized PatientsSensorsPhysical Activity Monitoringphysical activity; accelerometers; algorithm; validation; hospitalized patients10.3390/s21051652
Tanja E. Argillander, Vera van der Zanden, Hester J. van der Zaag-Loonen, K. Marieke Paarlberg, Wouter J. Meijer, Arnold-Jan Kruse, Henderik L. van Westreenen, Peter van Duijvendijk, Marian J.E. Mourits, Barbara C. van Munster2021Preoperative physical activity and frailty in older patients undergoing cancer surgery – PREsurgery studyJournal of Geriatric Oncology10.1016/j.jgo.2021.09.008
Darcy Ummels, Emmylou Beekman, Susy M. Braun, Anna J. Beurskens2021settings
Open AccessArticle
Using an Activity Tracker in Rehabilitation: Experiences of Healthcare Professionals and Patients
Int. J. Environ. Res. Public Healthe-Health Applicationsactivity tacker; eHealth; telehealth; implementation; experiences; meaningful use; clinical reasoning10.3390/ijerph18105147
Bogdan-Catalin Serban ,Octavian Buiu,Marius Bumbac ,Niculae Dumbravescu ,Viorel Avramescu,Mihai Brezeanu,Cristiana Radulescu ,Gabriel Craciun,Cristina Mihaela Nicolescu ,Cosmin Romanitan and Florin Comanescu2021Ternary Holey Carbon Nanohorns/TiO2/PVP Nanohybrids as Sensing Films for Resistive Humidity SensorsMDPIholey carbon nanohorns (CNHox); titanium (IV) oxide; polyvinylpyrrolidone (PVP); nanohybrid; resistive RH sensor; swelling
Wei Luo, Rick Kramer, Yvonne de Kort, Pascal Rense, Wouter van Marken Lichtenbelt2021The effects of a novel personal comfort system on thermal comfort, physiology and perceived indoor environmental quality, and its health implications - Stimulating human thermoregulation without compromising thermal comfortIndoor Airdrifting temperature, health, indoor air quality, personal comfort system, thermal comfort,
J. A. F. Demandt, L. J. Dubois, K. van Kuijk, M. Zaťovičová, H. Jin, S. Parkkila, S. W. van der Laan, L. Jelenska, B. M. E. Mees, C. P. M. Reutelingsperger, K. B. J. M. Cleutjens, C. J. H. van der Kallen, C. G. Schalkwijk, M. M. J. van Greevenbroek, E. A. L. Biessen, G. Pasterkamp, S. Pastoreková, C. D. A. Stehouwer & J. C. Sluimer2021The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular diseaseSpringer NatureAtherosclerosis , Cell death and immune response, Prognostic markers
Yoanna M.Ivanova, Hannah Pallubinsky, Rick Kramer, Wouter van Marken Lichtenbelt2021The influence of a moderate temperature drift on thermal physiology and perceptionPhysiology & BehaviorThermal physiology, Thermal comfort, Thermal sensation, Body temperature, Energy metabolism, Drifting temperature10.1016/j.physbeh.2020.113257
V. Filippou, A. C. Redmond, J. Bennion, M. R. Backhouse, D. Wong2020Capturing accelerometer outputs in healthy volunteers under normal and simulated-pathological conditions using ML classifiers*42nd Annual International Conference of the IEEE Engineering in Medicine & Biology SocietyPhysical Activity MonitoringAccelerometers,
Classification algorithms,
Task analysis,
Support vector machines, Machine learning algorithms
Johannes Essers, Alessio Murgia, Anneliek Peters, Kenneth Meijer
2020Daily Life Benefits and Usage Characteristics of Dynamic Arm Supports in Subjects with Neuromuscular DisordersSensorsUse of MOX in Upper Extremity ResearchNeuromuscular disorders
Dynamic arm support
Activity monitoring
Motor performance
Upper extremities
Yujiao Hao, Rong Zheng, Boyu Wang2020Invariant Feature Learning for Sensor-based Human Activity RecognitionIEEE Transactions of Mobile ComputingWearable sensor, Human activity recognition, Neural network, Meta-learning, Multi-task learning10.48550/arXiv.2012.07963
Darcy Ummels, Susy Braun, An Stevens, Emmylou Beekman, Anna Beurskens2020Measure It Super Simple (MISS) activity tracker: (re)design of a user-friendly interface and evaluation of experiences in daily lifeDisability and Rehabilitation: Assistive Technologye-Health ApplicationsWearable; elderly; interface;
experiences; user-centred
Joris Vangeneugden, Loek Verlaan, Pieter Oomen, Wai-Yan Liu, Marloes Peters, Nicole Natour, Pieter Emans, Kenneth Meijer2020Signatures of knee osteoarthritis in women in the temporal and fractal dynamics of human gaitClinical BiomechanicsKnee osteoarthritis; Obesity; Accelerometry; Activity pattern10.1016/j.clinbiomech.2020.105016
Hanneke C. van Dijk-Huisman, Anouk T.R. Weemaes, Tim A.E.J. Boymans, Antoine F. Lenssen, Rob A. de Bie 2020Smartphone App with an Accelerometer Enhances Patients’ Physical Activity Following Elective Orthopedic Surgery: A Pilot StudySensorse-Health Applicationsactivity monitoring
physical activity
functional recovery
wearable sensors
Adam Jake Sellers, Hannah Pallubinsky, Pascal Rense, Wouter Bijnens, Tineke van de Weijer, Esther Moonen-Kornips, Patrick Schrauwen, Wouter D. van Marken Lichtenbelt2020The effect of cold exposure with shivering on glucose tolerance in healthy men J Appl PhysiolPhysical Activity Monitoringcold-induced thermogenesis, glucose metabolism, insulin sensitivity, oral glucose tolerance test, thermoregulation10.1152/japplphysiol.00642.2020
Darcy Ummels, Wouter Bijnens, Jos Aarts, Kenneth Meijer, Anna J. Beurskens, Emmylou Beekman2020The Validation of a Pocket Worn Activity Tracker for Step Count and Physical Behavior in Older Adults during Simulated Activities of Daily LivingGerontology and Geriatric MedicineTechnical ValidationWearable, step count, physical activity, validation, older adults, ADL10.1177/2333721420951732
Bahcaci, U., & Demirbuken, I.2019Effects of chemotherapy process on postural balance control in patients with breast cancer.Indian J CancerPhysical Activity MonitoringAdult
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Breast Neoplasms/*drug therapy/pathology
Follow-Up Studies
Middle Aged
Postural Balance/drug effects/*physiology
Prospective Studies
Survivors/*statistics & numerical data
Breast neoplasms
postural balance
Bijnens, W., Aarts, J., Stevens, A., Ummels, D., & Meijer, K.2019Optimization and Validation of an Adjustable Activity Classification Algorithm for Assessment of Physical Behavior in Elderly.SensorsTechnical Validationaccelerometers
physical activity
sedentary behavior
Mesquita, R., Nakken, N., Janssen, D. J. A., van den Bogaart, E. H. A., Delbressine, J. M. L., Essers, J. M. N., Spruit, M. A.2017Activity Levels and Exercise Motivation in Patients With COPD and Their Resident Loved Ones.ChestPhysical Activity MonitoringCOPD
family caregivers
outcome assessment
physical activity
sedentary lifestyle
Mesquita, R., Meijer, K., Pitta, F., Azcuna, H., Go?rtz, Y. M. J., Essers, J. M. N., Spruit, M. A.2017Changes in physical activity and sedentary behaviour following pulmonary rehabilitation in patients with COPD.Respiratory MedicinePhysical Activity MonitoringChronic obstructive pulmonary disease
Physical activity
Outcome assessment (health care)
Koene, S., Dirks, I., van Mierlo, E., de Vries, P. R., Janssen, A. J. W. M., Smeitink, J. A. M., de Groot, I. J. M.2017Domains of Daily Physical Activity in Children with Mitochondrial Disease: A 3D Accelerometry Approach.JIMD reportsPhysical Activity Monitoring3D accelerometry
Daily physical activity
Mitochondrial disease
Outcome measures
van Roekel, E. H., Winkler, E. A., Bours, M. J., Lynch, B. M., Willems, P. J., Meijer, K., Weijenberg, M. P.2016Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors.Prev Med RepPhysical Activity MonitoringBMI, body mass index
CI, confidence interval
CIS, Checklist Individual Strength
CRC, colorectal cancer
Colorectal Neoplasms
EORTC QLQ-C30, European Organization for the Research and Treatment of Cancer
Quality of Life Questionnaire-Core 30
EnCoRe study, Energy for life after ColoRectal cancer study
HADS, Hospital Anxiety and Depression Scale
HRQoL, health-related quality of life
ICF, International Classification of Functioning, Disability and Health
MET, metabolic equivalent
MVPA, moderate-to-vigorous physical activity
Quality of Life
SD, standard deviation
Sedentary Lifestyle
WHO, World Health Organization
WHODAS II, 12-item World Health Organization Disability Assessment Schedule II
beta, unstandardized regression coefficient
van Roekel, E. H., Bours, M. J. L., Breedveld-Peters, J. J. L., Willems, P. J. B., Meijer, K., Kant, I., Weijenberg, M. P.2016Modeling how substitution of sedentary behavior with standing or physical activity is associated with health-related quality of life in colorectal cancer survivors.Cancer Causes & ControlPhysical Activity Monitoring010.1007/s10552-016-0725-6
van der Weegen, S., Essers, H., Spreeuwenberg, M., Verwey, R., Tange, H., de Witte, L., & Meijer, K.2015Concurrent validity of the MOX activity monitor compared to the ActiGraph GT3X.Telemed J E HealthTechnical ValidationAcceleration
*Activities of Daily Living
Case-Control Studies
Diabetes Mellitus, Type 2/*physiopathology
Equipment Design
Equipment Safety
Exercise Test/instrumentation
Healthy Volunteers
Linear Models
Middle Aged
Monitoring, Physiologic/*instrumentation
Pulmonary Disease, Chronic Obstructive/*physiopathology
Young Adult
diabetes mellitus
motor activity
pulmonary disease
Berendsen, B. A., Hendriks, M. R., Willems, P., Meijer, K., Schaper, N. C., & Savelberg, H. H.2014A 20 min window is optimal in a non-wear algorithm for tri-axial thigh-worn accelerometry in overweight people.Physiol MeasPhysical Activity MonitoringAccelerometry/*methods
Middle Aged
Monitoring, Ambulatory/*methods
Motor Activity
Reproducibility of Results
Time Factors
Berendsen, B. A., Hendriks, M. R., Meijer, K., Plasqui, G., Schaper, N. C., & Savelberg, H. H.2014Which activity monitor to use? Validity, reproducibility and user friendliness of three activity monitorsBMC Public HealthTechnical ValidationAccelerometry/*instrumentation
*Health Behavior
Monitoring, Ambulatory/*instrumentation
Patient Satisfaction/*statistics & numerical data
Reference Values
Reproducibility of Results
Surveys and Questionnaires
Young Adult
Annegarn, J., Spruit, M. A., Uszko-Lencer, N. H., Vanbelle, S., Savelberg, H. H., Schols, A. M., Meijer, K.2011Objective physical activity assessment in patients with chronic organ failure: a validation study of a new single-unit activity monitor.Arch Phys Med RehabilTechnical ValidationActivities of Daily Living
Chronic Disease
Heart Failure/*physiopathology
Middle Aged
Monitoring, Physiologic/*methods
Physical Therapy Modalities
Pulmonary Disease, Chronic Obstructive/*physiopathology
Reproducibility of Results