Research publications

The MOX is a validated and medically certified wearable accelerometer that delivers one of the most precise and consistent measurements for physical activity monitoring. It is the most advanced accelerometer development from Maastricht Instruments BV based on the earlier product versions, the CIRO Activity Monitor (CAM) and DAAFb which have been used for more than a decade to accurately measure physical activity in research and healthcare applications.

The publications are sorted by topic. The entire list can be viewed by clicking on next below the list.

AuthorsYear of PublicationTitleJournalTopicKeywordsDOI link
Hanneke C. van Dijk-Huisman, Mandy H. P. Welters, Wouter Bijnens, Sander M. J. van Kuijk, Fabienne J. H. Magdelijns, Robert A. de Bie, Antoine F. Lenssen 
2022Can telerehabilitation services combined with caregiver-mediated exercises improve early supported discharge services poststroke? A study protocol for a multicentre, observer-blinded, randomized controlled trial
BMC Neurology
Stroke, Telerehabilitation, Caregivers, Exercise, Walking, Clinical trial protocol
Hanneke C. van Dijk-Huisman, Mandy H. P. Welters, Wouter Bijnens, Sander M. J. van Kuijk, Fabienne J. H. Magdelijns, Robert A. de Bie, Antoine F. Lenssen 
2022Development and internal validation of a prediction model to identify older adults at risk of low physical activity levels during hospitalisation: a prospective cohort study
BMC Geriatrics
Physical activity, Hospital, Prediction model, Older adults
Irene Moll, Rik G. J. Marcellis, Marcel L. P. Coenen, Sabine M. Fleuren, Paul J. B. Willems, Lucianne A. W. M. Speth, M. Adhiambo Witlox, Kenneth Meijer, R. Jeroen Vermeulen 
2022A randomized crossover study of functional electrical stimulation during walking in spastic cerebral palsy: the FES on participation (FESPa) trial
BMC Pediatrics
Cerebral palsy, Spasticity, Gait, Orthoses, Functional electrical stimulation, Goal attainment scale
Ayan Chatterjee, Andreas Prinz2022Applying Spring Security Framework with KeyCloak-Based OAuth2 to Protect Microservice Architecture APIs: A Case Study
Data Security
API; REST; spring-boot; Keycloak; authentication; authorization; encryption; external attacks
Marlou-Floor Kenkhuis, Floortje Mols, Eline H. van Roekel, José J. L. Breedveld-Peters, Stéphanie O. Breukink, Maryska L. G. Janssen-Heijnen, Eric T. P. Keulen, Fränzel J. B. van Duijnhoven, Matty P. Weijenberg, Martijn J. L. Bours
2022Longitudinal Associations of Adherence to the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) Lifestyle Recommendations with Quality of Life and Symptoms in Colorectal Cancer Survivors up to 24 Months Post-Treatment
colorectal cancer survivorship; lifestyle recommendations; health-related quality of life; fatigue; chemotherapy-induced peripheral neuropathy
Ayan Chatterjee, Andreas Prinz, Martin Gerdes, Santiago Martinez, Nibedita Pahari, Yogesh Kumar Meena
2022ProHealth eCoach: User-Centered Design and Development of an eCoach App to Promote Healthy Lifestyle with Personalized Activity Recommendations
Research Square (Preprint)
eHealth Application
eCoach, User-Centered Design, Persuasive Strategies, Visualisation, Healthy Lifestyle, Physical Activity
Dieuwke van Dartel, Ying Wang, Johannes H. Hegeman, Marloes Vermeer, Miriam M.R. Vollenbroek-Hutten
2022Patterns of Physical Activity Over Time in Older Patients Rehabilitating after Hip Fracture Surgery: A Preliminary Study
medRxiv (preprint)

Patterns, physical activity, older patients, hip fracture rehabilitation, continuous monitoring
Līna Butāne, Liene Spilva-Ekerte, Andris Skride, Daina Šmite 2022Individually Tailored Remote Physiotherapy Program Improves Participation and Autonomy in Activities of Everyday Life along with Exercise Capacity, Self-Efficacy, and Low-Moderate Physical Activity in Patients with Pulmonary Arterial Hypertension: A Randomized Controlled StudyMedicinaRehabilitationchronic disease; pulmonary arterial hypertension; physiotherapy; individualized; interdisciplinary; quality of life; participation; exercise; physical activity; home-based; self-efficacy
Sophie Vanbelle, Emmanuel Lesaffre2021Modelling agreement for binary intensive longitudinal dataStatistical Modellingcontinuous recording, Reliability, time-event sequential data, time series, transient event10.1177/1471082X211034002
Kenkhuis, MF, van Roekel EH, Koole JL, Breedveld-Peters JJL, Breukink SO, Janssen-Heijnen MLG, Keulen ETP, van Duijnhoven FJB, Mols F, Weijenberg MP, Bours MJL2021Increases in adipose tissue and muscle function are longitudinally associated with better quality of life in colorectal cancer survivorsScientific ReportsCancer Survivors/psychology, Colorectal Neoplasms/complications, Longitudinal Studies, Quality of Life10.1038/s41598-021-91709-y
Yoanna M.Ivanova, Hannah Pallubinsky, Rick Kramer, Wouter van Marken Lichtenbelt2021The influence of a moderate temperature drift on thermal physiology and perceptionPhysiology & BehaviorThermal physiology, Thermal comfort, Thermal sensation, Body temperature, Energy metabolism, Drifting temperature10.1016/j.physbeh.2020.113257
Jeroen G. V. Habets, Margot Heijmans, Albert F. G. Leentjens, Claudia J. P. Simons, Yasin Temel, Mark L. Kuijf, Pieter L. Kubben, Christian Herff2021A Long-Term, Real-Life Parkinson Monitoring Database Combining Unscripted Objective and Subjective RecordingsDataParkinson’s disease; real-life; unscripted; naturalistic monitoring; wearable sensors; motor diaries; ecological momentary assessments; experience sampling method10.3390/data6020022
Marlou Floor Kenkhuis, Eline H. Van Roekel, José J.L. Breedveld-Peters, Stéphanie O. Breukink, Maryska L.G. Janssen-Heijnen, Eric T.P. Keulen, Fränzel J.B. Van Duijnhoven, Floortje Mols, Matty P. Weijnenberg, Martijn J.L. Bours2021Longitudinal Associations of Sedentary Behavior and Physical Activity with Quality of Life in Colorectal Cancer SurvivorsMedicine & Science in Sports & ExerciseColorectal cancer survivorship, Physical activity, Sedentary behaviour, Health-related quality of life, Fatigue, Chemotherapy-induced peripheral neuropathy10.1249/MSS.0000000000002703
Wei Luo, Rick Kramer, Yvonne de Kort, Pascal Rense, Wouter van Marken Lichtenbelt2021The effects of a novel personal comfort system on thermal comfort, physiology and perceived indoor environmental quality, and its health implications - Stimulating human thermoregulation without compromising thermal comfortIndoor Airdrifting temperature, health, indoor air quality, personal comfort system, thermal comfort,
Tanja E. Argillander, Vera van der Zanden, Hester J. van der Zaag-Loonen, K. Marieke Paarlberg, Wouter J. Meijer, Arnold-Jan Kruse, Henderik L. van Westreenen, Peter van Duijvendijk, Marian J.E. Mourits, Barbara C. van Munster2021Preoperative physical activity and frailty in older patients undergoing cancer surgery – PREsurgery studyJournal of Geriatric Oncology10.1016/j.jgo.2021.09.008
Darcy Ummels, Emmylou Beekman, Susy M. Braun, Anna J. Beurskens2021settings
Open AccessArticle
Using an Activity Tracker in Rehabilitation: Experiences of Healthcare Professionals and Patients
Int. J. Environ. Res. Public Healthe-Health Applicationsactivity tacker; eHealth; telehealth; implementation; experiences; meaningful use; clinical reasoning10.3390/ijerph18105147
Hanneke C. van Dijk-Huisman, Wouter Bijnens, Rachel Senden, Johannes M. N. Essers, Kenneth Meijer, Jos Aarts, Antoine F. Lenssen2021Optimization and Validation of a Classification Algorithm for Assessment of Physical Activity in Hospitalized PatientsSensorsPhysical Activity Monitoringphysical activity; accelerometers; algorithm; validation; hospitalized patients10.3390/s21051652
Yujiao Hao, Rong Zheng, Boyu Wang2020Invariant Feature Learning for Sensor-based Human Activity RecognitionIEEE Transactions of Mobile ComputingWearable sensor, Human activity recognition, Neural network, Meta-learning, Multi-task learning10.48550/arXiv.2012.07963
Joris Vangeneugden, Loek Verlaan, Pieter Oomen, Wai-Yan Liu, Marloes Peters, Nicole Natour, Pieter Emans, Kenneth Meijer2020Signatures of knee osteoarthritis in women in the temporal and fractal dynamics of human gaitClinical BiomechanicsKnee osteoarthritis; Obesity; Accelerometry; Activity pattern10.1016/j.clinbiomech.2020.105016
V. Filippou, A. C. Redmond, J. Bennion, M. R. Backhouse, D. Wong2020Capturing accelerometer outputs in healthy volunteers under normal and simulated-pathological conditions using ML classifiers*42nd Annual International Conference of the IEEE Engineering in Medicine & Biology SocietyPhysical Activity MonitoringAccelerometers,
Classification algorithms,
Task analysis,
Support vector machines, Machine learning algorithms
Yoanna M. Ivanova, Hannah Pallubinsky, Rick Kramer, Wouter van Marken Lichtenbelt2020The influence of a moderate temperature drift on thermal physiology and perceptionPhysiol. Behav.Physical Activity MonitoringThermal physiology; Thermal comfort; Thermal sensation; Body temperature; Energy metabolism; Drifting temperature10.1016/j.physbeh.2020.113257
Adam Jake Sellers, Hannah Pallubinsky, Pascal Rense, Wouter Bijnens, Tineke van de Weijer, Esther Moonen-Kornips, Patrick Schrauwen, Wouter D. van Marken Lichtenbelt2020The effect of cold exposure with shivering on glucose tolerance in healthy men J Appl PhysiolPhysical Activity Monitoringcold-induced thermogenesis, glucose metabolism, insulin sensitivity, oral glucose tolerance test, thermoregulation10.1152/japplphysiol.00642.2020
Darcy Ummels, Wouter Bijnens, Jos Aarts, Kenneth Meijer, Anna J. Beurskens, Emmylou Beekman2020The Validation of a Pocket Worn Activity Tracker for Step Count and Physical Behavior in Older Adults during Simulated Activities of Daily LivingGerontology and Geriatric MedicineTechnical ValidationWearable, step count, physical activity, validation, older adults, ADL10.1177/2333721420951732
Darcy Ummels, Susy Braun, An Stevens, Emmylou Beekman, Anna Beurskens2020Measure It Super Simple (MISS) activity tracker: (re)design of a user-friendly interface and evaluation of experiences in daily lifeDisability and Rehabilitation: Assistive Technologye-Health ApplicationsWearable; elderly; interface;
experiences; user-centred
Johannes Essers, Alessio Murgia, Anneliek Peters, Kenneth Meijer
2020Daily Life Benefits and Usage Characteristics of Dynamic Arm Supports in Subjects with Neuromuscular DisordersSensorsUse of MOX in Upper Extremity ResearchNeuromuscular disorders
Dynamic arm support
Activity monitoring
Motor performance
Upper extremities
Hanneke C. van Dijk-Huisman, Anouk T.R. Weemaes, Tim A.E.J. Boymans, Antoine F. Lenssen, Rob A. de Bie 2020Smartphone App with an Accelerometer Enhances Patients’ Physical Activity Following Elective Orthopedic Surgery: A Pilot StudySensorse-Health Applicationsactivity monitoring
physical activity
functional recovery
wearable sensors
Bijnens, W., Aarts, J., Stevens, A., Ummels, D., & Meijer, K.2019Optimization and Validation of an Adjustable Activity Classification Algorithm for Assessment of Physical Behavior in Elderly.SensorsTechnical Validationaccelerometers
physical activity
sedentary behavior
van der Weegen, S., Essers, H., Spreeuwenberg, M., Verwey, R., Tange, H., de Witte, L., & Meijer, K.2015Concurrent validity of the MOX activity monitor compared to the ActiGraph GT3X.Telemed J E HealthTechnical ValidationAcceleration
*Activities of Daily Living
Case-Control Studies
Diabetes Mellitus, Type 2/*physiopathology
Equipment Design
Equipment Safety
Exercise Test/instrumentation
Healthy Volunteers
Linear Models
Middle Aged
Monitoring, Physiologic/*instrumentation
Pulmonary Disease, Chronic Obstructive/*physiopathology
Young Adult
diabetes mellitus
motor activity
pulmonary disease
Berendsen, B. A., Hendriks, M. R., Meijer, K., Plasqui, G., Schaper, N. C., & Savelberg, H. H.2014Which activity monitor to use? Validity, reproducibility and user friendliness of three activity monitorsBMC Public HealthTechnical ValidationAccelerometry/*instrumentation
*Health Behavior
Monitoring, Ambulatory/*instrumentation
Patient Satisfaction/*statistics & numerical data
Reference Values
Reproducibility of Results
Surveys and Questionnaires
Young Adult
Annegarn, J., Spruit, M. A., Uszko-Lencer, N. H., Vanbelle, S., Savelberg, H. H., Schols, A. M., Meijer, K.2011Objective physical activity assessment in patients with chronic organ failure: a validation study of a new single-unit activity monitor.Arch Phys Med RehabilTechnical ValidationActivities of Daily Living
Chronic Disease
Heart Failure/*physiopathology
Middle Aged
Monitoring, Physiologic/*methods
Physical Therapy Modalities
Pulmonary Disease, Chronic Obstructive/*physiopathology
Reproducibility of Results
Bahcaci, U., & Demirbuken, I.2019Effects of chemotherapy process on postural balance control in patients with breast cancer.Indian J CancerPhysical Activity MonitoringAdult
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Breast Neoplasms/*drug therapy/pathology
Follow-Up Studies
Middle Aged
Postural Balance/drug effects/*physiology
Prospective Studies
Survivors/*statistics & numerical data
Breast neoplasms
postural balance
Koene, S., Dirks, I., van Mierlo, E., de Vries, P. R., Janssen, A. J. W. M., Smeitink, J. A. M., de Groot, I. J. M.2017Domains of Daily Physical Activity in Children with Mitochondrial Disease: A 3D Accelerometry Approach.JIMD reportsPhysical Activity Monitoring3D accelerometry
Daily physical activity
Mitochondrial disease
Outcome measures
Mesquita, R., Nakken, N., Janssen, D. J. A., van den Bogaart, E. H. A., Delbressine, J. M. L., Essers, J. M. N., Spruit, M. A.2017Activity Levels and Exercise Motivation in Patients With COPD and Their Resident Loved Ones.ChestPhysical Activity MonitoringCOPD
family caregivers
outcome assessment
physical activity
sedentary lifestyle
Mesquita, R., Meijer, K., Pitta, F., Azcuna, H., Goërtz, Y. M. J., Essers, J. M. N., Spruit, M. A.2017Changes in physical activity and sedentary behaviour following pulmonary rehabilitation in patients with COPD.Respiratory MedicinePhysical Activity MonitoringChronic obstructive pulmonary disease
Physical activity
Outcome assessment (health care)
van Roekel, E. H., Winkler, E. A., Bours, M. J., Lynch, B. M., Willems, P. J., Meijer, K., Weijenberg, M. P.2016Associations of sedentary time and patterns of sedentary time accumulation with health-related quality of life in colorectal cancer survivors.Prev Med RepPhysical Activity MonitoringBMI, body mass index
CI, confidence interval
CIS, Checklist Individual Strength
CRC, colorectal cancer
Colorectal Neoplasms
EORTC QLQ-C30, European Organization for the Research and Treatment of Cancer
Quality of Life Questionnaire-Core 30
EnCoRe study, Energy for life after ColoRectal cancer study
HADS, Hospital Anxiety and Depression Scale
HRQoL, health-related quality of life
ICF, International Classification of Functioning, Disability and Health
MET, metabolic equivalent
MVPA, moderate-to-vigorous physical activity
Quality of Life
SD, standard deviation
Sedentary Lifestyle
WHO, World Health Organization
WHODAS II, 12-item World Health Organization Disability Assessment Schedule II
beta, unstandardized regression coefficient
van Roekel, E. H., Bours, M. J. L., Breedveld-Peters, J. J. L., Willems, P. J. B., Meijer, K., Kant, I., Weijenberg, M. P.2016Modeling how substitution of sedentary behavior with standing or physical activity is associated with health-related quality of life in colorectal cancer survivors.Cancer Causes & ControlPhysical Activity Monitoring-10.1007/s10552-016-0725-6
Berendsen, B. A., Hendriks, M. R., Willems, P., Meijer, K., Schaper, N. C., & Savelberg, H. H.2014A 20 min window is optimal in a non-wear algorithm for tri-axial thigh-worn accelerometry in overweight people.Physiol MeasPhysical Activity MonitoringAccelerometry/*methods
Middle Aged
Monitoring, Ambulatory/*methods
Motor Activity
Reproducibility of Results
Time Factors